This section is for seriously unhinged people, or people with some need that can't be neatly handled. If you can, simply set your systems up so that they communicate with your ISP's mail server for POP and SMTP. You'll thank me for this advice. You really will.
You're still reading? OK, the reason for setting this up is that it gives you great control over how mail flows in and out of your system. In particular, it allows you to run alias lists without too much pain and catch mail going to yourself before it goes out into the big wide world. It also allows you to download mail from a single mailbox on your ISP and distribute it to several internal mailboxes or aliases. The reasons, and there are many, for not doing this are: